发明授权
- 专利标题： Polymeric derivative of cytidine metabolic antagonist
- 专利标题（中）： 胞苷代谢拮抗剂的聚合衍生物
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申请号： US11919912申请日： 2006-04-27
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公开(公告)号： US07700709B2公开(公告)日： 2010-04-20
- 发明人: Akira Masuda , Takeshi Onda , Hiroko Mashiba , Keiichirou Yamamoto , Kazutoshi Takashio
- 申请人： Akira Masuda , Takeshi Onda , Hiroko Mashiba , Keiichirou Yamamoto , Kazutoshi Takashio
- 申请人地址： JP Tokyo
- 专利权人： Nippon Kayaku Kabushiki Kaisha
- 当前专利权人： Nippon Kayaku Kabushiki Kaisha
- 当前专利权人地址： JP Tokyo
- 代理机构： Nields, Lemack & Frame, LLC
- 优先权： JP2005-138249 20050511
- 国际申请： PCT/JP2006/308826 WO 20060427
- 国际公布： WO2006/120914 WO 20061116
- 主分类号： C08G61/12
- IPC分类号： C08G61/12
摘要：
A derivative of a cytidine metabolic antagonist which can exert a high therapeutic effect at a low dose. A polymeric derivative of a cytidine metabolic antagonist which comprises a polymeric compound having a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a cytidine metabolic antagonist, which has such a structure that the carboxyl group in the side chain of the polymeric compound and an amino group in the cytidine metabolic antagonist are bound together to form an amide bond.
公开/授权文献
- US20090012252A1 Polymeric Derivative of Cytidine Metabolic Antagonist 公开/授权日：2009-01-08
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