发明授权
- 专利标题: Antibodies directed to HER-3 and uses thereof
- 专利标题(中): 针对HER-3的抗体及其用途
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申请号: US11649722申请日: 2007-01-03
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公开(公告)号: US07705130B2公开(公告)日: 2010-04-27
- 发明人: Mike Rothe , Martin Treder , Susanne Hartmann , Eric Borges , Larry L. Green
- 申请人: Mike Rothe , Martin Treder , Susanne Hartmann , Eric Borges , Larry L. Green
- 申请人地址: DE Martinsried US CA Thousand Oaks
- 专利权人: U3 Pharma GmbH,Amgen, Inc.
- 当前专利权人: U3 Pharma GmbH,Amgen, Inc.
- 当前专利权人地址: DE Martinsried US CA Thousand Oaks
- 代理机构: Fish & Richardson P.C.
- 主分类号: C07K16/00
- IPC分类号: C07K16/00
摘要:
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.
公开/授权文献
- US20080124345A1 Antibodies directed to HER-3 and uses thereof 公开/授权日:2008-05-29
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