发明授权
- 专利标题: Anaerobic bacterium as a drug for cancer gene therapy
- 专利标题(中): 厌氧菌作为癌基因治疗药物
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申请号: US10782899申请日: 2004-02-23
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公开(公告)号: US07740835B2公开(公告)日: 2010-06-22
- 发明人: Minoru Fujimori , Shun'ichiro Taniguchi , Jun Amano , Kazuyuki Yazawa , Yasunobu Kano , Toshiyuki Nakamura , Takayuki Sasaki
- 申请人: Minoru Fujimori , Shun'ichiro Taniguchi , Jun Amano , Kazuyuki Yazawa , Yasunobu Kano , Toshiyuki Nakamura , Takayuki Sasaki
- 申请人地址: JP Tokyo
- 专利权人: Anaeropharma Science Inc.
- 当前专利权人: Anaeropharma Science Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Jones Day
- 优先权: JP2000-287688 20000921
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12P21/04 ; C12N15/85
摘要:
The present invention provides a bacterium belonging to the genus Bifidobacterium, by which DNA coding for a protein having an antitumor activity or DNA coding for a protein having the activity of converting a precursor of an antitumor substance into the antitumor substance is delivered to tumor tissues specifically under anaerobic conditions thereby expressing the protein encoded by the DNA, as well as a pharmaceutical composition comprising said anaerobic bacterium.
公开/授权文献
- US20050025745A1 Anaerobic bacterium as a drug for cancer gene therapy 公开/授权日:2005-02-03