Invention Grant
- Patent Title: Pyridazine derivatives and their use as therapeutic agents
- Patent Title (中): 哒嗪衍生物及其作为治疗剂的用途
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Application No.: US11055034Application Date: 2005-02-09
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Publication No.: US07754711B2Publication Date: 2010-07-13
- Inventor: Nagasree Chakka , Mikhail Chafeev , Sultan Chowdhury , Jian-Min Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Shifeng Liu , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Michael D. Winther , Zaihui Zhang , Melwyn Abreo , Mark W. Holladay , Wenbao Li , Sengen Sun , Chi Tu , Heinz W. Gschwend
- Applicant: Nagasree Chakka , Mikhail Chafeev , Sultan Chowdhury , Jian-Min Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Shifeng Liu , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Michael D. Winther , Zaihui Zhang , Melwyn Abreo , Mark W. Holladay , Wenbao Li , Sengen Sun , Chi Tu , Heinz W. Gschwend
- Applicant Address: CA Burnaby, British Columbia
- Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee: Xenon Pharmaceuticals Inc.
- Current Assignee Address: CA Burnaby, British Columbia
- Agency: Osha • Liang LLP
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5513 ; A61K31/50 ; A61K31/502 ; A61K31/501 ; C07D245/02 ; C07D243/04 ; C07D243/08 ; C07D403/04 ; C07D401/14 ; C07D403/14 ; A61P7/12
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (Ia): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Public/Granted literature
- US20060009459A1 Pyridazine derivatives and their use as therapeutic agents Public/Granted day:2006-01-12
Information query
