发明授权
- 专利标题: 4-benzimidazol-2-ylpyridazin-3-one derivatives
- 专利标题(中): 4-苯并咪唑-2-基哒嗪-3-酮衍生物
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申请号: US12251572申请日: 2008-10-15
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公开(公告)号: US07754713B2公开(公告)日: 2010-07-13
- 发明人: Swen Hoelder , Karl Schoenafinger , David William Will , Hans Matter , Gunter Muller , Cecile Combeau , Christine Delaisi , Anke Steinmetz , Ingrid Sassoon
- 申请人: Swen Hoelder , Karl Schoenafinger , David William Will , Hans Matter , Gunter Muller , Cecile Combeau , Christine Delaisi , Anke Steinmetz , Ingrid Sassoon
- 申请人地址: FR Antony
- 专利权人: Aventis Pharma S.A.
- 当前专利权人: Aventis Pharma S.A.
- 当前专利权人地址: FR Antony
- 代理商 Kelly L. Bender
- 优先权: DE102004010207 20040302
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; A61K31/5355 ; A61P35/00 ; C07D401/14 ; C07D403/04 ; C07D413/14
摘要:
Disclosed are compounds of the general formula (I), where the definition of the substituents A, B, D, E, R1 and R2 are detailed in the description, and the physiologically tolerated salts thereof, a process for the preparation of these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase CDK2 (cyclin-dependent kinase 2).
公开/授权文献
- US20090042880A1 NOVEL 4-BENZIMIDAZOL-2-YLPYRIDAZIN-3-ONE DERIVATIVES 公开/授权日:2009-02-12
信息查询
IPC分类: