发明授权
- 专利标题： Modulators of CFTR
- 专利标题（中）： CFTR调制器
-
申请号： US12117948申请日： 2008-05-09
-
公开(公告)号： US07754739B2公开(公告)日： 2010-07-13
- 发明人: Sara S. Hadida Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- 申请人： Sara S. Hadida Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Michael J. Diverdi
- 主分类号： A61K31/4418
- IPC分类号： A61K31/4418 ; A61K31/443 ; C07D405/02 ; C07D213/72
摘要：
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
公开/授权文献
- US20080286204A1 MODULATORS OF CFTR 公开/授权日：2008-11-20
信息查询
IPC分类:
