Invention Grant
- Patent Title: N-acylsulfonamide apoptosis promoters
- Patent Title (中): N-酰基磺酰胺凋亡启动子
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Application No.: US12364987Application Date: 2009-02-03
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Publication No.: US07754886B2Publication Date: 2010-07-13
- Inventor: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J Hajduk , Aaron R Kunzer , William J. Mcclellan , David D. Nettesheim , Thorsten K. Oost , Andrew M. Petros , Saul Howard Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Applicant: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J Hajduk , Aaron R Kunzer , William J. Mcclellan , David D. Nettesheim , Thorsten K. Oost , Andrew M. Petros , Saul Howard Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Oona A. Manzari
- Main IPC: C07C211/00
- IPC: C07C211/00 ; A61K31/445
Abstract:
N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.
Public/Granted literature
- US20090137585A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS Public/Granted day:2009-05-28
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