Invention Grant
- Patent Title: Method of the invention preparations of factor IXa
- Patent Title (中): 本发明的方法制备因子IXa
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Application No.: US12221086Application Date: 2008-07-30
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Publication No.: US07767647B2Publication Date: 2010-08-03
- Inventor: Shane Donovan , Donald Baker
- Applicant: Shane Donovan , Donald Baker
- Applicant Address: US IL Deerfield CH Glattpark (Opfikon)
- Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee Address: US IL Deerfield CH Glattpark (Opfikon)
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The invention provides a method of treating bleeding disorders in a subject by administration of a preparation enriched for Factor IXa. The Factor IXa can be produced by proteolytically activating recombinantly-produced Factor IX. The invention also provides an improved method for producing Factor IXa from a plasma fraction, which method results in a Factor IXa product containing little or no prekallikrein activity, thus reducing the incidence of undesired side effects in a subject.
Public/Granted literature
- US20090069543A1 Factor IXa for the treatment of bleeding disorders Public/Granted day:2009-03-12
Information query
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