发明授权
- 专利标题: Evolving new molecular function
- 专利标题(中): 进化新分子功能
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申请号: US10950367申请日: 2004-09-24
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公开(公告)号: US07771935B2公开(公告)日: 2010-08-10
- 发明人: David R. Liu , Zev J. Gartner , Christopher T. Calderone
- 申请人: David R. Liu , Zev J. Gartner , Christopher T. Calderone
- 申请人地址: US MA Cambridge
- 专利权人: President and Fellows of Harvard College
- 当前专利权人: President and Fellows of Harvard College
- 当前专利权人地址: US MA Cambridge
- 代理机构: Goodwin Procter LLP
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis.
公开/授权文献
- US20050170376A1 Evolving new molecular function 公开/授权日:2005-08-04
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