发明授权
- 专利标题: Bacterial ion channel
- 专利标题(中): 细菌离子通道
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申请号: US10494783申请日: 2002-11-05
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公开(公告)号: US07790845B2公开(公告)日: 2010-09-07
- 发明人: David Clapham , Dejian Ren
- 申请人: David Clapham , Dejian Ren
- 申请人地址: US MA Boston
- 专利权人: Children's Medical Center Corporation
- 当前专利权人: Children's Medical Center Corporation
- 当前专利权人地址: US MA Boston
- 代理机构: Nixon Peabody LLP
- 国际申请: PCT/US02/35395 WO 20021105
- 国际公布: WO03/040323 WO 20030515
- 主分类号: C07K14/195
- IPC分类号: C07K14/195
摘要:
The present invention relates to a functionally expressed bacterial voltage-sensitive ion-selective channel. The novel channel can be used in conjunction with mammalian ion channel pore-containing regions in assays for screening for compounds that modulate activity of the channel. One bacterial ion channel of the present invention, called NaChBac, is derived from Bacillus halodurans (GenBank#BAB05220 (8)).
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