发明授权
- 专利标题： Nucleotide mimics and their prodrugs
- 专利标题（中）： 核苷酸模拟物及其前药
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申请号： US11818666申请日： 2007-06-14
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公开(公告)号： US07807653B2公开(公告)日： 2010-10-05
- 发明人: Phillip D. Cook , Guangyi Wang , Thomas W. Bruice , Nicholas A. Boyle , Janet M. Leeds , Jennifer L. Brooks , Marija Prhavc , Maria Eugenia Ariza , Patrick C. Fagan , Yi Jin , Vivek K. Rajwanshi , Kathleen D. Tucker
- 申请人： Phillip D. Cook , Guangyi Wang , Thomas W. Bruice , Nicholas A. Boyle , Janet M. Leeds , Jennifer L. Brooks , Marija Prhavc , Maria Eugenia Ariza , Patrick C. Fagan , Yi Jin , Vivek K. Rajwanshi , Kathleen D. Tucker
- 申请人地址： AU Notting Hill, Victoria
- 专利权人： Biota Scientific Management Pty Ltd
- 当前专利权人： Biota Scientific Management Pty Ltd
- 当前专利权人地址： AU Notting Hill, Victoria
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K31/7076
- IPC分类号： A61K31/7076 ; A61K31/708 ; C07H19/20
摘要：
The present invention relates to nucleoside diphosphate mimics and nucleoside triphosphate mimics, which contain diphosphate or triphosphate moiety mimics and optionally sugar-modifications and/or base-modifications. The nucleotide mimics of the present invention, in a form of a pharmaceutically acceptable salt, a pharmaceutically acceptable prodrug, or a pharmaceutical formulation, are useful as antiviral, antimicrobial, and anticancer agents. The present invention provides a method for the treatment of viral infections, microbial infections, and proliferative disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of the present invention optionally in combination with other pharmaceutically active agents.
公开/授权文献
- US20070265224A1 Nucleotide mimics and their prodrugs 公开/授权日：2007-11-15
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