发明授权
US07846435B1 Humanized antibodies that recognize Verotoxin II and cell line producing same
有权
识别Verotoxin II和产生相同的细胞系的人源化抗体
- 专利标题: Humanized antibodies that recognize Verotoxin II and cell line producing same
- 专利标题(中): 识别Verotoxin II和产生相同的细胞系的人源化抗体
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申请号: US09700851申请日: 1999-05-19
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公开(公告)号: US07846435B1公开(公告)日: 2010-12-07
- 发明人: Yoh-Ichi Matsumoto , Atsuchi Imaizumi , Tsuyoshi Kimura , Tae Takeda , Man Sung Co , Maximiliano Vasquez
- 申请人: Yoh-Ichi Matsumoto , Atsuchi Imaizumi , Tsuyoshi Kimura , Tae Takeda , Yoshifumi Takeda, legal representative , Man Sung Co , Maximiliano Vasquez
- 申请人地址: JP Tokyo US NV Incline Village
- 专利权人: Teijin Limited,PDL Biopharma, Inc.
- 当前专利权人: Teijin Limited,PDL Biopharma, Inc.
- 当前专利权人地址: JP Tokyo US NV Incline Village
- 代理机构: Townsend and Townsend and Crew LLP
- 国际申请: PCT/US99/11179 WO 19990519
- 国际公布: WO99/59629 WO 19991125
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K39/40 ; A61K39/02
摘要:
The invention provides humanized antibodies that specifically bind to, and preferably, neutralize, verotoxin II (VT2). The antibodies are useful for treating patients suffering from, or at risk of suffering, toxic effects of verotoxin.
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