发明授权
- 专利标题： Drug-polymer conjugates coupled to a peptidic carrier
- 专利标题（中）： 与肽载体偶联的药物 - 聚合物共轭物
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申请号： US11816317申请日： 2006-02-16
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公开(公告)号： US07846893B2公开(公告)日： 2010-12-07
- 发明人: Patrick J. Sinko , Stanley Stein , Simi Gunaseelan , Shahriar Pooyan , Li Wan , Xiaoping Zhang
- 申请人： Patrick J. Sinko , Stanley Stein , Simi Gunaseelan , Shahriar Pooyan , Li Wan , Xiaoping Zhang
- 申请人地址： US NJ New Brunswick
- 专利权人： Rutgers, The State University of New Jersey
- 当前专利权人： Rutgers, The State University of New Jersey
- 当前专利权人地址： US NJ New Brunswick
- 代理机构： Fox Rothschild LLP
- 代理商 Peter J. Butch, III; Shahnam Sharareh
- 国际申请： PCT/US2006/005729 WO 20060216
- 国际公布： WO2006/089156 WO 20060824
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/06 ; A61K38/08 ; A01N25/34
摘要：
Monodisperse macromolecular conjugate compositions of a peptidic carrier irreversibly or reversibly conjugated with one or more effectors and one or more therapeutic agents, wherein at least one effector or therapeutic agent is attached to a pendant reactive group on said peptidic carrier via a water-soluble polymer. Monodispersity is obtained through the use of orthogonal and separate conjugation reactions.
公开/授权文献
- US20080188399A1 Drug-Polymer Conjugates Coupled to a Peptidic Carrier 公开/授权日：2008-08-07