发明授权
- 专利标题： Compositions and methods for increasing telomerase activity
- 专利标题（中）： 用于增加端粒酶活性的组合物和方法
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申请号： US10562374申请日： 2004-06-23
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公开(公告)号： US07846904B2公开(公告)日： 2010-12-07
- 发明人: Calvin Bruce Harley , Allison C. Chin , Tsutomu Akama , Nancy Yuk-yu Ip , Yung-hou Wong , David M. Miller-Martini
- 申请人： Calvin Bruce Harley , Allison C. Chin , Tsutomu Akama , Nancy Yuk-yu Ip , Yung-hou Wong , David M. Miller-Martini
- 申请人地址： US CA Menlo Park
- 专利权人： Geron Corporation
- 当前专利权人： Geron Corporation
- 当前专利权人地址： US CA Menlo Park
- 代理商 Leslie A. Mool; David J. Earp
- 国际申请： PCT/US2004/020277 WO 20040623
- 国际公布： WO2005/000245 WO 20050106
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; A01N45/00
摘要：
The present invention relates to methods for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The method and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin aliments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells.
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