发明授权
- 专利标题： Piperidine and morpholine renin inhibitors
- 专利标题（中）： 哌啶和吗啉肾素抑制剂
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申请号： US12225986申请日： 2007-04-05
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公开(公告)号： US07858624B2公开(公告)日： 2010-12-28
- 发明人: John J. Baldwin , David A. Claremon , Colin M. Tice , Salvacion Cacatian , Lawrence W. Dillard , Alexey V. Ishchenko , Jing Yuan , Zhenrong Xu , Gerard McGeehan , Wei Zhao , Robert D. Simpson , Suresh B. Singh
- 申请人： John J. Baldwin , David A. Claremon , Colin M. Tice , Salvacion Cacatian , Lawrence W. Dillard , Alexey V. Ishchenko , Jing Yuan , Zhenrong Xu , Gerard McGeehan , Wei Zhao , Robert D. Simpson , Suresh B. Singh
- 申请人地址： US PA Fort Washington
- 专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人地址： US PA Fort Washington
- 代理机构： Hamilton, Brook, Smith & Reynolds, P.C.
- 国际申请： PCT/US2007/008521 WO 20070405
- 国际公布： WO2007/117560 WO 20071018
- 主分类号： A61K31/5355
- IPC分类号： A61K31/5355 ; A61K31/4402 ; A61K31/4525 ; A61K31/445 ; C07D411/12 ; C07D213/30 ; C07D403/12 ; C07D405/12 ; C07D401/12 ; C07D211/22
摘要：
Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.
公开/授权文献
- US20090264432A1 Piperidine and Morpholine Renin Inhibitors 公开/授权日：2009-10-22
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