发明授权
US07872134B2 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
失效
2 - {[2-(取代氨基)乙基]磺酰基}乙基N,N-双(2-氯乙基)磷酰胺
- 专利标题: 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
- 专利标题(中): 2 - {[2-(取代氨基)乙基]磺酰基}乙基N,N-双(2-氯乙基)磷酰胺
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申请号: US11955177申请日: 2007-12-12
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公开(公告)号: US07872134B2公开(公告)日: 2011-01-18
- 发明人: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- 申请人: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- 申请人地址: US CA Palo Alto
- 专利权人: Telik, Inc.
- 当前专利权人: Telik, Inc.
- 当前专利权人地址: US CA Palo Alto
- 代理机构: Foley & Lardner LLP
- 主分类号: C07F9/572
- IPC分类号: C07F9/572 ; C07F9/576 ; C07F9/24 ; A61K31/664 ; A61K31/675
摘要:
2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.
公开/授权文献
- US20090156559A1 2-ethyl N,N-bis(2-chloroethyl)phosphorodiamidates 公开/授权日:2009-06-18
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