发明授权
- 专利标题： DNA ligase mutants
- 专利标题（中）： DNA连接酶突变体
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申请号： US11473272申请日： 2006-06-23
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公开(公告)号： US07927853B2公开(公告)日： 2011-04-19
- 发明人: Hirokazu Nishida , Yoshizumi Ishino , Kosuke Morikawa
- 申请人： Hirokazu Nishida , Yoshizumi Ishino , Kosuke Morikawa
- 申请人地址： JP Tokyo
- 专利权人： Hitachi, Ltd.
- 当前专利权人： Hitachi, Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Stites & Harbison PLLC
- 代理商 Juan Carlos A. Marquez, Esq.
- 优先权： JP2005-232360 20050810
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C12N9/00
摘要：
It is intended to obtain DNA ligase improved in binding ability and reactivity with DNA, particularly thermostable DNA ligase improved in binding ability and reactivity with DNA. The present invention provides a DNA ligase mutant improved in binding ability and reactivity with DNA, which is obtained by partially or completely deleting a C-terminal helix portion of DNA ligase. Particularly, the mutant is derived from a thermostable bacterium.
公开/授权文献
- US20070037190A1 DNA ligase mutants 公开/授权日：2007-02-15
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