发明授权
US07968099B2 Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer
有权
核酸和相应的标题为193P1E1B的蛋白质可用于治疗和检测癌症
- 专利标题： Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer
- 专利标题（中）： 核酸和相应的标题为193P1E1B的蛋白质可用于治疗和检测癌症
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申请号： US12648854申请日： 2009-12-29
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公开(公告)号： US07968099B2公开(公告)日： 2011-06-28
- 发明人: Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
- 申请人： Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
A novel gene (designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 193P1E1B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 193P1E1B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 191P1E1B can be used in active or passive immunization.
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