发明授权
- 专利标题： Polymorphic and amorphous salt forms of squalamine dilactate
- 专利标题（中）： 多形态和无定形盐形式的角鲨烷稀释液
-
申请号： US11410098申请日： 2006-04-25
-
公开(公告)号： US07981876B2公开(公告)日： 2011-07-19
- 发明人: Eric Chellquist , Mary Doubleday , Charles Gilbert , Xuehai Zhang , Michael McLane , Kyle Armbruster , Roy C. Levitt
- 申请人： Eric Chellquist , Mary Doubleday , Charles Gilbert , Xuehai Zhang , Michael McLane , Kyle Armbruster , Roy C. Levitt
- 申请人地址： US NY New York
- 专利权人： Ohr Pharmaceuticals, Inc.
- 当前专利权人： Ohr Pharmaceuticals, Inc.
- 当前专利权人地址： US NY New York
- 代理机构： Morgan Lewis & Bockius LLP
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; C07J41/00
摘要：
The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation.