发明授权
- 专利标题: Therapeutic compounds
- 专利标题(中): 治疗化合物
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申请号: US12218425申请日: 2008-07-15
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公开(公告)号: US07989438B2公开(公告)日: 2011-08-02
- 发明人: Immacolata Conte , Joerg Habermann , Angela Mackay , Frank Narjes , Maria del Rosario Rico Ferreira , Ian Stansfield
- 申请人: Immacolata Conte , Joerg Habermann , Angela Mackay , Frank Narjes , Maria del Rosario Rico Ferreira , Ian Stansfield
- 申请人地址: IT Rome
- 专利权人: Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA
- 当前专利权人: Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA
- 当前专利权人地址: IT Rome
- 代理商 Sheldon O. Heber; Julia M. Lake
- 优先权: GBGB0713865.4 20070717; GBGB0724635.8 20071219
- 主分类号: C07D513/18
- IPC分类号: C07D513/18 ; C07D513/22 ; C07D515/22 ; A61K31/4155 ; A61K31/454 ; A61K31/5517 ; A61P31/12
摘要:
A class of macrocyclic compounds of formula (I), wherein R7, A, Ar, B, D, F, M, Q1, Q2, W, X, Y and Z are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection.
公开/授权文献
- US20090048239A1 Therapeutic compounds 公开/授权日:2009-02-19
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