发明授权
- 专利标题: Microfluidic droplet queuing network
- 专利标题(中): 微流控液滴排队网络
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申请号: US12097455申请日: 2007-02-07
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公开(公告)号: US07993911B2公开(公告)日: 2011-08-09
- 发明人: Mark Davies , Tara Dalton , Julie Garvey , Kieran Curran , Damian Curtin
- 申请人: Mark Davies , Tara Dalton , Julie Garvey , Kieran Curran , Damian Curtin
- 申请人地址: IE Limerick
- 专利权人: Stokes Bio Limited
- 当前专利权人: Stokes Bio Limited
- 当前专利权人地址: IE Limerick
- 国际申请: PCT/IE2007/000014 WO 20070207
- 国际公布: WO2007/091229 WO 20070816
- 主分类号: C12M1/34
- IPC分类号: C12M1/34
摘要:
A multi-port liquid bridge (1) adds aqueous phase droplets (10) in an enveloping oil phase carrier liquid (11) to a draft channel (4, 6). A chamber (3) links four ports, and it is permanently full of oil (11) when in use. Oil phase is fed in a draft flow from an inlet port (4) and exits through a draft exit port (6) and a compensating flow port (7). The oil carrier and the sample droplets (3) (“aqueous phase”) flow through the inlet port (5) with an equivalent fluid flow subtracted through the compensating port (7). The ports of the bridge (1) are formed by the ends of capillaries held in position in plastics housings. The phases are density matched to create an environment where gravitational forces are negligible. This results in droplets (10) adopting spherical forms when suspended from capillary tube tips. Furthermore, the equality of mass flow is equal to the equality of volume flow. The phase of the inlet flow (from the droplet inlet port (5) and the draft inlet port (4) is used to determine the outlet port (6) flow phase.
公开/授权文献
- US20100015606A1 MICROFLUIDIC DROPLET QUEUING NETWORK 公开/授权日:2010-01-21