发明授权
US07998949B2 Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
有权
双环杂环,含有所述化合物的药物,其用途及其生产方法
- 专利标题: Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
- 专利标题(中): 双环杂环,含有所述化合物的药物,其用途及其生产方法
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申请号: US12525742申请日: 2008-01-30
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公开(公告)号: US07998949B2公开(公告)日: 2011-08-16
- 发明人: Frank Himmelsbach , Birgit Jung , Ralf Lotz , Markus Ostermeier
- 申请人: Frank Himmelsbach , Birgit Jung , Ralf Lotz , Markus Ostermeier
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Edward S. Lazer
- 优先权: EP07101785 20070206; EP07118700 20071017
- 国际申请: PCT/EP2008/051141 WO 20080130
- 国际公布: WO2008/095847 WO 20080814
- 主分类号: A61K31/517
- IPC分类号: A61K31/517
摘要:
The present invention relates to bicyclic heterocycles of general formula wherein Ra, Rb and Rc are defined as in claim 1, their tautomers, their stereoisomers, their mixtures and their salts, in particular their physiologically acceptable salts with inorganic or organic acids and bases, which have valuable pharmacological properties, in particular an inhibitory action on the signal transduction mediated by tyrosine kinases, their use for the treatment of illnesses, in particular of tumoral diseases and of benign prostatic hyperplasia (BPH), of diseases of the lung and of the airways, and the preparation thereof.
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