Invention Grant
- Patent Title: Histamine H3-receptor ligands and their therapeutic application
- Patent Title (中): 组胺H3受体配体及其治疗应用
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Application No.: US11912812Application Date: 2006-04-26
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Publication No.: US08017646B2Publication Date: 2011-09-13
- Inventor: Isabelle Bertrand , Marc Capet , Jeanne-Marie Lecomte , Nicolas Levoin , Xavier Ligneau , Olivia Poupardin-Olivier , Philippe Robert , Jean-Charles Schwartz
- Applicant: Isabelle Bertrand , Marc Capet , Jeanne-Marie Lecomte , Nicolas Levoin , Xavier Ligneau , Olivia Poupardin-Olivier , Philippe Robert , Jean-Charles Schwartz
- Applicant Address: FR Paris
- Assignee: Bioprojet
- Current Assignee: Bioprojet
- Current Assignee Address: FR Paris
- Agency: Stites & Harbison PLLC
- Agent B. Aaron Schulman, Esq.; Terry L. Wright, Esq.
- Priority: EP05290948 20050429
- International Application: PCT/IB2006/001018 WO 20060426
- International Announcement: WO2006/117611 WO 20061109
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D207/08
Abstract:
The present patent application concerns new compounds of formula (I) with R1 and R2 taken together with the nitrogen atom to which they are attached, form a saturated nitrogen-containing ring, A is a saturated C1-4 alkylene and B a C3-4 alkylene or alkenylene chain; their preparation and their use as a H3 receptor ligand for treating e.g. CNS disorders like Alzheimer's disease.
Public/Granted literature
- US20080182876A1 Histamine H3-Receptor Ligands and Their Therapeutic Application Public/Granted day:2008-07-31
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