发明授权
- 专利标题: Triazole derivative
- 专利标题(中): 三唑衍生物
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申请号: US12278054申请日: 2007-02-05
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公开(公告)号: US08022091B2公开(公告)日: 2011-09-20
- 发明人: Naoya Ono , Tetsuo Takayama , Fumiyasu Shiozawa , Hironori Katakai , Tetsuya Yabuuchi , Tomomi Ota , Makoto Yagi , Masakazu Sato
- 申请人: Naoya Ono , Tetsuo Takayama , Fumiyasu Shiozawa , Hironori Katakai , Tetsuya Yabuuchi , Tomomi Ota , Makoto Yagi , Masakazu Sato
- 申请人地址: JP Tokyo
- 专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2006-027799 20060203
- 国际申请: PCT/JP2007/051951 WO 20070205
- 国际公布: WO2007/089018 WO 20070809
- 主分类号: A01N43/64
- IPC分类号: A01N43/64 ; A61K31/41 ; C07D249/12
摘要:
An object of the present invention is to provide a compound having an action of inhibiting binding between S1P and its receptor, Edg-1 (S1P1), and is useful as a pharmaceutical compound. A compound or a pharmaceutically acceptable salt thereof, which compound is represented by the formula below (where A represents an oxygen atom, a sulfur atom, a group represented by Formula —SO—, a group represented by Formula —SO2—, or the like, R1 represents a hydrogen atom, an alkyl group having 1-6 carbon atoms, or the like, R1A represents a hydrogen atom or the like, R2 represents an alkyl group having 1-6 carbon atoms, a cycloalkyl group having 3-6 carbon atoms, or the like, R3 represents an aryl group, R4 represents a hydrogen atom or an alkyl group having 1-6 carbon atoms and optionally substituted with a carboxyl group, and R5 represents an alkyl group having 1-10 carbon atoms, a cycloalkyl group having 3-8 carbon atoms, an aryl group which is optionally substituted, or the like).
公开/授权文献
- US20100041655A1 TRIAZOLE DERIVATIVE 公开/授权日:2010-02-18
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