发明授权
US08036835B2 Probe design methods and microarrays for comparative genomic hybridization and location analysis
有权
用于比较基因组杂交和位置分析的探针设计方法和微阵列
- 专利标题： Probe design methods and microarrays for comparative genomic hybridization and location analysis
- 专利标题（中）： 用于比较基因组杂交和位置分析的探针设计方法和微阵列
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申请号： US12797521申请日： 2010-06-09
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公开(公告)号： US08036835B2公开(公告)日： 2011-10-11
- 发明人: Nicholas M. Sampas , Bo Curry , Peter Tsang , Doron Lipson , Zohar H. Yakhini
- 申请人： Nicholas M. Sampas , Bo Curry , Peter Tsang , Doron Lipson , Zohar H. Yakhini
- 申请人地址： US CA Santa Clara
- 专利权人： Agilent Technologies, Inc.
- 当前专利权人： Agilent Technologies, Inc.
- 当前专利权人地址： US CA Santa Clara
- 代理机构： Bozicevic, Field & Francis
- 代理商 James S. Keddie; Bret E. Field
- 主分类号： G06F7/00
- IPC分类号： G06F7/00
摘要：
Methods and systems for identifying and selecting nucleic acid probes for detecting a target with a nucleic acid probe array or comparative genome hybridization microarray, comprising selecting a plurality of potential target sequences, generating a plurality of candidate probes from the target sequences, filtering the plurality of candidate probes by analyzing candidate probes for selected probe properties in silico. Microarrays comprising probes selected by the methods of the invention are particularly useful for comparative genome hybridization and location analysis.
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