发明授权
US08039000B2 Nucleic acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer
失效
核酸和相应的标题为158P3D2的蛋白质可用于治疗和检测癌症
- 专利标题： Nucleic acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer
- 专利标题（中）： 核酸和相应的标题为158P3D2的蛋白质可用于治疗和检测癌症
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申请号： US11483354申请日： 2006-07-06
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公开(公告)号： US08039000B2公开(公告)日： 2011-10-18
- 发明人: Aya Jakobovits , Mary Faris , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Rene S. Hubert , Daniel E. H. Afar , Wangmao Ge , Arthur B. Raitano , Pia M. Challita-Eid
- 申请人： Aya Jakobovits , Mary Faris , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Rene S. Hubert , Daniel E. H. Afar , Wangmao Ge , Arthur B. Raitano , Pia M. Challita-Eid
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
A novel gene (designated 158P3D2) and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.