- 专利标题: Kappa opioid receptor ligands
-
申请号: US12105814申请日: 2008-04-18
-
公开(公告)号: US08048895B2公开(公告)日: 2011-11-01
- 发明人: Frank Ivy Carroll , Hernan A. Navarro , James B. Thomas , Tingwei Cai
- 申请人: Frank Ivy Carroll , Hernan A. Navarro , James B. Thomas , Tingwei Cai
- 申请人地址: US NC Research Triangle Park
- 专利权人: Research Triangle Institute
- 当前专利权人: Research Triangle Institute
- 当前专利权人地址: US NC Research Triangle Park
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; C07D251/00 ; C07D401/00 ; C07D271/00 ; C07D487/00
摘要:
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.
公开/授权文献
- US20090264462A1 KAPPA OPIOID RECEPTOR LIGANDS 公开/授权日:2009-10-22
信息查询
IPC分类: