发明授权
US08093016B2 Use of an aspartic protease (NS24) signal sequence for heterologous protein expression
有权
使用天冬氨酸蛋白酶(NS24)信号序列进行异源蛋白质表达
- 专利标题: Use of an aspartic protease (NS24) signal sequence for heterologous protein expression
- 专利标题(中): 使用天冬氨酸蛋白酶(NS24)信号序列进行异源蛋白质表达
-
申请号: US12600652申请日: 2008-05-21
-
公开(公告)号: US08093016B2公开(公告)日: 2012-01-10
- 发明人: Marguerite A. Cervin , Steven Kim
- 申请人: Marguerite A. Cervin , Steven Kim
- 申请人地址: US CA Palo Alto
- 专利权人: Danisco US Inc.
- 当前专利权人: Danisco US Inc.
- 当前专利权人地址: US CA Palo Alto
- 国际申请: PCT/US2008/006498 WO 20080521
- 国际公布: WO2008/150376 WO 20081211
- 主分类号: C12P21/06
- IPC分类号: C12P21/06 ; C12N15/00 ; C12N1/20 ; C07H21/02 ; C07K1/00
摘要:
The invention relates to heterologous polypeptide expression and secretion by filamentous fungi and vectors and processes for expression and secretion of such polypeptides. More particularly, the invention discloses the use of a signal sequence form an aspartic protease obtained from Trichoderma and referred to as an NSP24 signal sequence.