发明授权
- 专利标题： Anti-PERP recombinant antibody
- 专利标题（中）： 抗PERP重组抗体
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申请号： US11634209申请日： 2006-12-06
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公开(公告)号： US08093362B2公开(公告)日： 2012-01-10
- 发明人: Atsushi Ochiai , Emi Hosaka , Kazuyasu Nakamura , Akiko Furuya , Yuji Ohki
- 申请人： Atsushi Ochiai , Emi Hosaka , Kazuyasu Nakamura , Akiko Furuya , Yuji Ohki
- 申请人地址： JP Tokyo JP Tokyo
- 专利权人： Kyowa Hakko Kirin Co., Ltd.,Japan as Represented by President of National Cancer Center
- 当前专利权人： Kyowa Hakko Kirin Co., Ltd.,Japan as Represented by President of National Cancer Center
- 当前专利权人地址： JP Tokyo JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JPP.2005-352297 20051206
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C12P21/08 ; C12P21/04 ; A61K39/395 ; A61K39/00
摘要：
An antibody which binds to a polypeptide encoded by human PERP (p53 apoptosis effector related to PMP-22) gene which is considered to be related to incidence of cancer or the like is desired. The present invention provides a gene recombinant antibody which has no consensus sequence of an N-linked sugar chain in a variable region, specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by the PERP gene and binds to the extracellular region. The antibody is useful for treatment of various diseases expressing a polypeptide encoded by the PERP gene.
公开/授权文献
- US20080267953A1 Anti-perp recombinant antibody 公开/授权日：2008-10-30