Invention Grant
- Patent Title: Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams
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Application No.: US12948284Application Date: 2010-11-17
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Publication No.: US08097162B2Publication Date: 2012-01-17
- Inventor: Edward F. Leonard , Alan C. West , Christian Paul Aucoin , Edgar E. Nanne
- Applicant: Edward F. Leonard , Alan C. West , Christian Paul Aucoin , Edgar E. Nanne
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Miles & Stockbridge, P.C.
- Agent Mark A. Catan
- Main IPC: B01D61/38
- IPC: B01D61/38 ; B01D61/24 ; B01D61/14 ; B01D11/00 ; A61M1/34 ; A61M37/00

Abstract:
A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration.
Public/Granted literature
- US20110062083A1 SYSTEMS AND METHODS OF MICROFLUIDIC MEMBRANELESS EXCHANGE USING FILTRATION OF EXTRACTION OUTLET STREAMS Public/Granted day:2011-03-17
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