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公开(公告)号：US20120219483A1
公开(公告)日：2012-08-30
申请号：US13453300
申请日：2012-04-23
Applicant: Klaus S. Lackner , Alan C. West , Jennifer L. Wade
Inventor： Klaus S. Lackner , Alan C. West , Jennifer L. Wade
IPC: B01D53/62 , B01J27/232
CPC classification number: B01D53/228 , B01D67/0041 , B01D67/0088 , B01D69/142 , B01D71/02 , B01D71/024 , B01D2256/22 , B01D2258/0208 , B01D2323/08 , C04B35/48 , C04B38/061 , C04B2111/00801 , C04B2235/6025 , H01M8/0668 , H01M2008/1293 , Y02C10/04 , Y02C10/10 , C04B38/0054
Abstract: A carbon dioxide permeable membrane is described. In some embodiments, the membrane includes a body having a first side and an opposite second side; a plurality of first regions formed from a molten carbonate having a temperature of about 400 degrees Celsius to about 1200 degrees Celsius, the plurality of first regions forming a portion of the body and the plurality of first regions extending from the first side of the body to the second side of the body; a plurality of second regions formed from an oxygen conductive solid oxide, the plurality of second regions combining with the plurality of first regions to form the body and the plurality of second regions extending from the first side of the body to the second side of the body; and the body is configured to allow carbon dioxide to pass from the first side to the second side.
Abstract translation: 描述了二氧化碳可渗透膜。 在一些实施例中，膜包括具有第一侧和相对的第二侧的主体; 由熔融碳酸盐形成的多个第一区域，其具有约400摄氏度至约1200摄氏度的温度，所述多个第一区域形成所述主体的一部分，并且所述多个第一区域从所述主体的第一侧延伸到 身体的第二面 由氧传导性固体氧化物形成的多个第二区域，所述多个第二区域与所述多个第一区域结合以形成所述主体，并且所述多个第二区域从所述主体的第一侧向所述主体的第二侧延伸 ; 并且所述主体构造成允许二氧化碳从所述第一侧通过到所述第二侧。
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公开(公告)号：US08163065B2
公开(公告)日：2012-04-24
申请号：US13052392
申请日：2011-03-21
Applicant: Klaus S. Lackner , Alan C. West , Jennifer L. Wade
Inventor： Klaus S. Lackner , Alan C. West , Jennifer L. Wade
IPC: B01D53/22
CPC classification number: B01D53/228 , B01D67/0041 , B01D67/0088 , B01D69/142 , B01D71/02 , B01D71/024 , B01D2256/22 , B01D2258/0208 , B01D2323/08 , C04B35/48 , C04B38/061 , C04B2111/00801 , C04B2235/6025 , H01M8/0668 , H01M2008/1293 , Y02C10/04 , Y02C10/10 , C04B38/0054
Abstract: A carbon dioxide permeable membrane is described. In some embodiments, the membrane includes a body having a first side and an opposite second side; a plurality of first regions formed from a molten carbonate having a temperature of about 400 degrees Celsius to about 1200 degrees Celsius, the plurality of first regions forming a portion of the body and the plurality of first regions extending from the first side of the body to the second side of the body; a plurality of second regions formed from an oxygen conductive solid oxide, the plurality of second regions combining with the plurality of first regions to form the body and the plurality of second regions extending from the first side of the body to the second side of the body; and the body is configured to allow carbon dioxide to pass from the first side to the second side.
Abstract translation: 描述了二氧化碳可渗透膜。 在一些实施例中，膜包括具有第一侧和相对的第二侧的主体; 由熔融碳酸盐形成的多个第一区域，其具有约400摄氏度至约1200摄氏度的温度，所述多个第一区域形成所述主体的一部分，并且所述多个第一区域从所述主体的第一侧延伸到 身体的第二面 由导电固体氧化物形成的多个第二区域，所述多个第二区域与所述多个第一区域结合以形成所述主体，并且所述多个第二区域从所述主体的第一侧延伸到所述主体的第二侧 ; 并且所述主体构造成允许二氧化碳从所述第一侧通过到所述第二侧。
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公开(公告)号：US20100004578A1
公开(公告)日：2010-01-07
申请号：US12499038
申请日：2009-07-07
Applicant: Edward F. Leonard , Alan C. West , Nina C. Shapley , Zhongliang Tang
Inventor： Edward F. Leonard , Alan C. West , Nina C. Shapley , Zhongliang Tang
IPC: A61M1/14
CPC classification number: A61M1/14 , A61M2206/11 , B01D11/0288 , B01D11/0492 , B01D11/0496 , B01L3/5027
Abstract: The present invention is directed to devices, systems and methods for removing undesirable materials from a sample fluid by contact with a second fluid. The sample fluid flows as a thin layer adjacent to, or between, concurrently flowing layers of the second fluid, without an intervening membrane. In various embodiments, a secondary separator is used to restrict the removal of desirable substances and effect the removal of undesirable substances from blood. The invention is useful in a variety of situations where a sample fluid is to be purified via a diffusion mechanism against an extractor fluid. Moreover, the invention may be used for the removal of components from a sample fluid that vary in size. When blood is the sample fluid, for example, this may include the removal of small molecules, middle molecules, macromolecules, macromolecular aggregates, and cells, from the blood sample to the extractor fluid.
Abstract translation: 本发明涉及通过与第二流体接触从样品流体中除去不需要的材料的装置，系统和方法。 样品流体作为与第二流体的同时流动的层相邻或相邻的薄层流动，而没有中间膜。 在各种实施方案中，使用次级分离器来限制所需物质的去除并且实现从血液中除去不需要的物质。 本发明可用于各种情况，其中样品液体经由针对抽提流体的扩散机制进行纯化。 此外，本发明可用于从尺寸变化的样品流体中除去组分。 例如，当血液是样品液体时，这可能包括从血液样品到提取液中去除小分子，中分子，大分子，大分子聚集体和细胞。
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公开(公告)号：US06802950B2
公开(公告)日：2004-10-12
申请号：US10304175
申请日：2002-11-26
Applicant: John T. Hachman, Jr. , James J. Kelly , Alan C. West
Inventor： John T. Hachman, Jr. , James J. Kelly , Alan C. West
IPC: C25D2112
CPC classification number: C25D17/008 , C25D17/001
Abstract: The use of an insulating shield for improving the current distribution in an electrochemical plating bath is disclosed. Numerical analysis is used to evaluate the influence of shield shape and position on plating uniformity. Simulation results are compared to experimental data for nickel deposition from a nickel—sulfamate bath. The shield is shown to improve the average current density at a plating surface.
Abstract translation: 公开了使用绝缘屏蔽来改善电化学电镀槽中的电流分布。 数值分析用于评估屏蔽形状和位置对电镀均匀性的影响。 将仿真结果与来自镍 - 氨基磺酸盐浴的镍沉积的实验数据进行比较。 屏蔽显示可以提高电镀表面的平均电流密度。
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公开(公告)号：US20120292253A1
公开(公告)日：2012-11-22
申请号：US13566592
申请日：2012-08-03
Applicant: Edward F. Leonard , Alan C. West , Christian P. Aucoin , Edgar E. Nanne
Inventor： Edward F. Leonard , Alan C. West , Christian P. Aucoin , Edgar E. Nanne
CPC classification number: A61M1/14 , A61M1/1696 , A61M1/32 , A61M2205/7563 , A61M2206/11 , B01D11/0492 , B01D11/0496 , G01N2030/0045
Abstract: A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration.
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Patent Agency Ranking
公开(公告)号：US08097162B2
公开(公告)日：2012-01-17
申请号：US12948284
申请日：2010-11-17
Applicant: Edward F. Leonard , Alan C. West , Christian Paul Aucoin , Edgar E. Nanne
Inventor： Edward F. Leonard , Alan C. West , Christian Paul Aucoin , Edgar E. Nanne
CPC classification number: A61M1/14 , A61M1/1696 , A61M1/32 , A61M2205/7563 , A61M2206/11 , B01D11/0492 , B01D11/0496 , G01N2030/0045
Abstract: A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration.
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7.发明申请公开(公告)号：US20110056884A1
公开(公告)日：2011-03-10
申请号：US12942519
申请日：2010-11-09
Applicant: Edward F. LEONARD , Alan C. WEST , Nina C. SHAPLEY , Zhongliang TANG
Inventor： Edward F. LEONARD , Alan C. WEST , Nina C. SHAPLEY , Zhongliang TANG
IPC: B01D61/26
CPC classification number: A61M1/14 , A61M1/1696 , A61M1/32 , A61M1/3482 , A61M1/3621 , A61M2206/11 , B01D11/04 , B01D11/0496 , B01D61/243 , B01D61/28 , B01L3/5027 , G01N2001/4016 , Y10T436/255
Abstract: The present invention is directed to devices, systems and methods for removing undesirable materials from a sample fluid by contact with a second fluid. The sample fluid flows as a thin layer adjacent to, or between, concurrently flowing layers of the second fluid, without an intervening membrane. In various embodiments, a secondary separator is used to restrict the removal of desirable substances and effect the removal of undesirable substances from blood. The invention is useful in a variety of situations where a sample fluid is to be purified via a diffusion mechanism against an extractor fluid. Moreover, the invention may be used for the removal of components from a sample fluid that vary in size. When blood is the sample fluid, for example, this may include the removal of ‘small’ molecules, ‘middle’ molecules, macromolecules, macromolecular aggregates, and cells, from the blood sample to the extractor fluid.
Abstract translation: 本发明涉及通过与第二流体接触从样品流体中除去不需要的材料的装置，系统和方法。 样品流体作为与第二流体的同时流动的层相邻或相邻的薄层流动，而没有中间膜。 在各种实施方案中，使用次级分离器来限制所需物质的去除并且实现从血液中除去不需要的物质。 本发明可用于各种情况，其中样品液体经由针对抽提流体的扩散机制进行纯化。 此外，本发明可用于从尺寸变化的样品流体中除去组分。 当血液是样品液体时，例如，这可能包括从血液样品到提取液中去除“小”分子，“中”分子，大分子，大分子聚集体和细胞。
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公开(公告)号：US20100051474A1
公开(公告)日：2010-03-04
申请号：US12548893
申请日：2009-08-27
Applicant: Panayotis C. Andricacos , Caliopi Andricacos , Donald F. Canaperi , Emanuel I. Cooper , John M. Cotte , Hariklia Deligianni , Laertis Economikos , Daniel C. Edelstein , Silvia Franz , Balasubramanian Pranatharthiharan , Mahadevaiyer Krishnan , Andrew P. Mansson , Erick G. Walton , Alan C. West
Inventor： Panayotis C. Andricacos , Caliopi Andricacos , Donald F. Canaperi , Emanuel I. Cooper , John M. Cotte , Hariklia Deligianni , Laertis Economikos , Daniel C. Edelstein , Silvia Franz , Balasubramanian Pranatharthiharan , Mahadevaiyer Krishnan , Andrew P. Mansson , Erick G. Walton , Alan C. West
IPC: B23H5/06
CPC classification number: C25F3/02 , B23H5/08 , C09G1/04 , H01L21/32125
Abstract: Methods and compositions for electro-chemical-mechanical polishing (e-CMP) of silicon chip interconnect materials, such as copper, are provided. The methods include the use of compositions according to the invention in combination with pads having various configurations.
Abstract translation: 提供了诸如铜之类的硅芯片互连材料的电化学机械抛光（e-CMP）的方法和组合物。 所述方法包括使用根据本发明的组合物与具有各种构型的垫组合。
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9.发明申请SYSTEMS AND METHODS OF MICROFLUIDIC MEMBRANELESS EXCHANGE USING FILTRATION OF EXTRACTION OUTLET STREAMS 失效使用过滤出口流程进行微流控膜交换的系统和方法公开(公告)号：US20090139931A1
公开(公告)日：2009-06-04
申请号：US11814117
申请日：2007-05-22
Applicant: Edward F. Leonard , Alan C. West , Christian P. Aucoin , Edgar E. Nanne
Inventor： Edward F. Leonard , Alan C. West , Christian P. Aucoin , Edgar E. Nanne
CPC classification number: A61M1/14 , A61M1/1696 , A61M1/32 , A61M2205/7563 , A61M2206/11 , B01D11/0492 , B01D11/0496 , G01N2030/0045
Abstract: A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration.
Abstract translation: 一种通过在微流体通道中直接接触来在第一和第二流体之间交换部件的装置，系统和方法。 流体在通道中以薄层流动。 一个流体在离开通道后通过过滤器，并通过改变流体性质的二次处理器再循环。 再循环的液体被重新用于进一步交换。 过滤器从再循环流体排除血细胞，并防止或限制过滤器的堵塞。 二次处理器通过渗滤除去代谢废物和水。
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公开(公告)号：US20090101008A1
公开(公告)日：2009-04-23
申请号：US11874707
申请日：2007-10-18
Applicant: Klaus S. Lackner , Alan C. West , Jennifer L. Wade
Inventor： Klaus S. Lackner , Alan C. West , Jennifer L. Wade
CPC classification number: B01D53/228 , B01D67/0041 , B01D67/0088 , B01D69/142 , B01D71/02 , B01D71/024 , B01D2256/22 , B01D2258/0208 , B01D2323/08 , C04B35/48 , C04B38/061 , C04B2111/00801 , C04B2235/6025 , H01M8/0668 , H01M2008/1293 , Y02C10/04 , Y02C10/10 , C04B38/0054
Abstract: A carbon dioxide permeable membrane is described. In some embodiments, the membrane includes a body having a first side and an opposite second side; a plurality of first regions formed from a molten carbonate having a temperature of about 400 degrees Celsius to about 1200 degrees Celsius, the plurality of first regions forming a portion of the body and the plurality of first regions extending from the first side of the body to the second side of the body; a plurality of second regions formed from an oxygen conductive solid oxide, the plurality of second regions combining with the plurality of first regions to form the body and the plurality of second regions extending from the first side of the body to the second side of the body; and the body is configured to allow carbon dioxide to pass from the first side to the second side.
Abstract translation: 描述了二氧化碳可渗透膜。 在一些实施例中，膜包括具有第一侧和相对的第二侧的主体; 由熔融碳酸盐形成的多个第一区域，其具有约400摄氏度至约1200摄氏度的温度，所述多个第一区域形成所述主体的一部分，并且所述多个第一区域从所述主体的第一侧延伸到 身体的第二面 由导电固体氧化物形成的多个第二区域，所述多个第二区域与所述多个第一区域结合以形成所述主体，并且所述多个第二区域从所述主体的第一侧延伸到所述主体的第二侧 ; 并且所述主体构造成允许二氧化碳从所述第一侧通过到所述第二侧。
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