发明授权
US08106069B2 Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them
有权
作为激酶抑制剂活性的吡咯并[2,3-b]吡啶衍生物和包含它们的药物组合物
![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them](/docs/US/2012-01-31/US08106069B2/abs.jpg.600x600.jpg)
- 专利标题： Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them
- 专利标题（中）： 作为激酶抑制剂活性的吡咯并[2,3-b]吡啶衍生物和包含它们的药物组合物
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申请号： US12766230申请日： 2010-04-23
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公开(公告)号： US08106069B2公开(公告)日： 2012-01-31
- 发明人: Barbara Salom , Matteo D'Anello , Maria Gabriella Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Arthur Brookfield , William John Trigg , Edward Andrew Boyd , Jonathan Anthony Larard
- 申请人： Barbara Salom , Matteo D'Anello , Maria Gabriella Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Arthur Brookfield , William John Trigg , Edward Andrew Boyd , Jonathan Anthony Larard
- 申请人地址： IT Rome
- 专利权人： Pfizer Italia S.r.l.
- 当前专利权人： Pfizer Italia S.r.l.
- 当前专利权人地址： IT Rome
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/50 ; A61K31/497 ; A61K31/445
![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them](/abs-image/US/2012/01/31/US08106069B2/abs.jpg.150x150.jpg)
摘要：
Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
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