发明授权
- 专利标题: Expanding the eukaryotic genetic code
- 专利标题(中): 扩大真核遗传密码
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申请号: US11978121申请日: 2007-10-26
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公开(公告)号: US08114628B2公开(公告)日: 2012-02-14
- 发明人: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- 申请人: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- 申请人地址: US CA La Jolla
- 专利权人: The Scripps Research Institute
- 当前专利权人: The Scripps Research Institute
- 当前专利权人地址: US CA La Jolla
- 代理机构: Quine Intellectual Property Law Group, P.C.
- 代理商 Christina Onufryk
- 主分类号: C12P21/06
- IPC分类号: C12P21/06 ; C12N9/10 ; C12N1/20
摘要:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献
- US20080227195A1 Expanding the eukaryotic genetic code 公开/授权日:2008-09-18
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