发明授权
US08114865B2 Indazole derivatives as kinase inhibitors for the treatment of cancer
有权
吲唑衍生物作为治疗癌症的激酶抑制剂
- 专利标题： Indazole derivatives as kinase inhibitors for the treatment of cancer
- 专利标题（中）： 吲唑衍生物作为治疗癌症的激酶抑制剂
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申请号： US12520387申请日： 2007-12-14
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公开(公告)号： US08114865B2公开(公告)日： 2012-02-14
- 发明人: Tiziano Bandiera , Andrea Lombardi Borgia , Marcella Nesi , Ettore Perrone , Roberto Bossi , Paolo Polucci
- 申请人： Tiziano Bandiera , Andrea Lombardi Borgia , Marcella Nesi , Ettore Perrone , Roberto Bossi , Paolo Polucci
- 申请人地址： IT Nerviano (MI)
- 专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人地址： IT Nerviano (MI)
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 优先权： EP06126701 20061220
- 国际申请： PCT/EP2007/063998 WO 20071214
- 国际公布： WO2008/074749 WO 20080626
- 主分类号： A61K31/415
- IPC分类号： A61K31/415 ; A61K31/497 ; A61K31/445 ; A61K31/44 ; A61K31/40 ; C07D243/08 ; C07D403/12 ; C07D211/32 ; C07D401/12 ; C07D231/56
摘要：
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a dysregulated protein kinase activity, like cancer formula (I).
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