发明授权
US08133865B2 von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
有权
von Willebrand因子和因子VIII-聚合物缀合物具有可释放的连接
- 专利标题： von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
- 专利标题（中）： von Willebrand因子和因子VIII-聚合物缀合物具有可释放的连接
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申请号： US12006059申请日： 2007-12-27
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公开(公告)号： US08133865B2公开(公告)日： 2012-03-13
- 发明人: Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
- 申请人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
- 申请人地址： US CA San Francisco US IL Deerfield CH Wallisellen
- 专利权人： Nektar Therapeutics,Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人： Nektar Therapeutics,Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人地址： US CA San Francisco US IL Deerfield CH Wallisellen
- 代理机构： King & Spalding LLP
- 代理商 Susan T. Evans; Mark A. Wilson
- 主分类号： A61K38/36
- IPC分类号： A61K38/36 ; C07K14/755
摘要：
The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
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