发明授权
US08148070B2 Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
有权
与冠状动脉事件和药物反应相关的遗传多态性，检测方法及其用途
- 专利标题： Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
- 专利标题（中）： 与冠状动脉事件和药物反应相关的遗传多态性，检测方法及其用途
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申请号： US12569475申请日： 2009-09-29
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公开(公告)号： US08148070B2公开(公告)日： 2012-04-03
- 发明人: Olga Iakoubova , James J. Devlin , Carmen Tong , Charles Rowland
- 申请人： Olga Iakoubova , James J. Devlin , Carmen Tong , Charles Rowland
- 申请人地址： US CA Alameda
- 专利权人： Celera Corporation
- 当前专利权人： Celera Corporation
- 当前专利权人地址： US CA Alameda
- 代理机构： Celera Corporation
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34
摘要：
The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
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