Invention Grant
US08148396B2 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
有权
三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
- Patent Title: Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
- Patent Title (中): 三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
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Application No.: US12424674Application Date: 2009-04-16
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Publication No.: US08148396B2Publication Date: 2012-04-03
- Inventor: James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
- Applicant: James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Terence J. Bogie
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D513/02
Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof wherein W, L, R3, R3a, R3b and R4 are defined herein.
Public/Granted literature
- US20090203668A1 TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS Public/Granted day:2009-08-13
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