发明授权
- 专利标题: Sulfonamides as TRPM8 modulators
- 专利标题(中): 磺酰胺作为TRPM8调节剂
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申请号: US12175740申请日: 2008-07-18
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公开(公告)号: US08153682B2公开(公告)日: 2012-04-10
- 发明人: Shawn T. Branum , Raymond W. Colburn , Scott L. Dax , Christopher M. Flores , Michele C. Jetter , Yi Liu , Donald Ludovici , Mark J. Macielag , Jay M. Matthews , James J. McNally , Laura M. Reaney , Ronald K. Russell , Ning Qin , Christopher Teleha , Kenneth M. Wells , Scott C. Youells , Mark A. Youngman
- 申请人: Shawn T. Branum , Raymond W. Colburn , Scott L. Dax , Christopher M. Flores , Michele C. Jetter , Yi Liu , Donald Ludovici , Mark J. Macielag , Jay M. Matthews , James J. McNally , Laura M. Reaney , Ronald K. Russell , Ning Qin , Christopher Teleha , Kenneth M. Wells , Scott C. Youells , Mark A. Youngman
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica, NV
- 当前专利权人: Janssen Pharmaceutica, NV
- 当前专利权人地址: BE
- 主分类号: C07D419/12
- IPC分类号: C07D419/12 ; C07D417/12 ; C07D413/12 ; C07D409/04 ; C07D409/12 ; C07D333/66 ; A61K31/5377 ; A61K31/496 ; A61K31/4535 ; A61K31/433 ; A61K31/4245 ; A61K31/422 ; A61K31/4196 ; A61K31/4192 ; A61K31/4178 ; A61K31/4025 ; A61K31/381
摘要:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1, R2, R3, and R4 are defined herein.
公开/授权文献
- US20090264474A1 SULFONAMIDES AS TRPM8 MODULATORS 公开/授权日:2009-10-22
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