发明授权
US08168422B2 Microorganism producing inosine and method of producing inosine using the same
有权
生产肌苷的微生物及使用其产生肌苷的方法
- 专利标题： Microorganism producing inosine and method of producing inosine using the same
- 专利标题（中）： 生产肌苷的微生物及使用其产生肌苷的方法
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申请号： US12522004申请日： 2008-01-15
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公开(公告)号： US08168422B2公开(公告)日： 2012-05-01
- 发明人: Young-hoon Park , Kwang-myung Cho , Hee-jong Lee , Jin-nam Lee
- 申请人： Young-hoon Park , Kwang-myung Cho , Hee-jong Lee , Jin-nam Lee
- 申请人地址： KR Seoul
- 专利权人： CJ Cheiljedang Corporation
- 当前专利权人： CJ Cheiljedang Corporation
- 当前专利权人地址： KR Seoul
- 代理机构： Swanson & Bratschun, L.L.C.
- 优先权： KR10-2007-0004341 20070115
- 国际申请： PCT/KR2008/000236 WO 20080115
- 国际公布： WO2008/088156 WO 20080724
- 主分类号： C12P19/40
- IPC分类号： C12P19/40 ; C12N9/00 ; C12N1/20 ; C12N15/00 ; C07H21/04
摘要：
The present invention relates to a microorganism producing inosine, which is one of purine nucleoside, an important material for 5′-inosinic acid synthesis, and method for producing inosine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus producing inosine at high concentration by inactivating the gene encoding nucleoside hydrolase II and by enhancing the expression of the gene encoding 5′-nucleotidase, which still retains the characteristics of Corynebacterium ammoniagenes CJIP2401 (KCCM-10610).
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