发明授权
US08168771B2 Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants
有权
使用共有序列作为疫苗抗原来增强对毒性病毒变体的识别
- 专利标题： Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants
- 专利标题（中）： 使用共有序列作为疫苗抗原来增强对毒性病毒变体的识别
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申请号： US11815203申请日： 2006-01-31
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公开(公告)号： US08168771B2公开(公告)日： 2012-05-01
- 发明人: Stuart C. Ray , Andrew L. Cox , David L. Thomas
- 申请人： Stuart C. Ray , Andrew L. Cox , David L. Thomas
- 申请人地址： US MD Baltimore
- 专利权人： The Johns Hopkins University
- 当前专利权人： The Johns Hopkins University
- 当前专利权人地址： US MD Baltimore
- 代理机构： Banner & Witcoff, Ltd
- 国际申请： PCT/US2006/003514 WO 20060131
- 国际公布： WO2006/086188 WO 20060817
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; A61K39/29
摘要：
The invention provides consensus sequences for hepatitis C virus 1a and 1b. Also provided are non-synonymous changes for each residue of the consensus sequences. These sequences are useful as compositions or vaccines for prophylactic use or treating HCV-infected individuals. Also provided are methods for lessening the chances for a HCV-infected individual to enter a chronic phase of infection and methods of diagnosing an individual with HCV 1a or HCV 1b infection.
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