发明授权
- 专利标题： Evolving new molecular function
- 专利标题（中）： 进化新分子功能
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申请号： US12834072申请日： 2010-07-12
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公开(公告)号： US08206914B2公开(公告)日： 2012-06-26
- 发明人: David R. Liu , Zev J. Gartner , Jeffrey B. Doyon , Christopher T. Calderone , Matthew W. Kanan , Xiaoyu Li , Thomas M. Snyder , Daniel M. Rosenbaum
- 申请人： David R. Liu , Zev J. Gartner , Jeffrey B. Doyon , Christopher T. Calderone , Matthew W. Kanan , Xiaoyu Li , Thomas M. Snyder , Daniel M. Rosenbaum
- 申请人地址： US MA Cambridge
- 专利权人： President and Fellows of Harvard College
- 当前专利权人： President and Fellows of Harvard College
- 当前专利权人地址： US MA Cambridge
- 代理机构： Goodwin Procter LLP
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis.
公开/授权文献
- US20110190141A1 Evolving New Molecular Function 公开/授权日：2011-08-04
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