Invention Grant
- Patent Title: Pharmaceutical process and intermediates 714
- Patent Title (中): 制药工艺和中间体714
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Application No.: US12830577Application Date: 2010-07-06
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Publication No.: US08227622B2Publication Date: 2012-07-24
- Inventor: Debra Ainge , Eric Merifield , Colin Thomson , Michael Butters , Ravi Ramakrishnan , Ravi Naidu Rayapati , Parhalad Ray Sharma
- Applicant: Debra Ainge , Eric Merifield , Colin Thomson , Michael Butters , Ravi Ramakrishnan , Ravi Naidu Rayapati , Parhalad Ray Sharma
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Fish & Richardson P.C.
- Main IPC: C07D209/30
- IPC: C07D209/30 ; C07D209/12
Abstract:
The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): X is ═O, ═N—OH or ═N—OC(O)Me; Y is hydrogen, PhS- or p-chlorophenylsulfanyl; Z is hydrogen or —CH2COOR1 wherein R1 is selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.
Public/Granted literature
- US20110046394A1 Pharmaceutical Process and Intermediates 714 Public/Granted day:2011-02-24
Information query
