A method for forming a plurality of variable linewidth spacers adjoining a plurality of uniformly spaced topographic features uses a conformal resist layer upon a spacer material layer located over the plurality of uniformly spaced topographic features. The conformal resist layer is differentially exposed and developed to provide a differential thickness resist layer that is used as a sacrificial mask when forming the variable linewidth spacers. A method for forming uniform linewidth spacers adjoining narrowly spaced topographic features and widely spaced topographic features over the same substrate uses a masked isotropic etching of a variable thickness spacer material layer to provide a more uniform partially etched spacer material layer, followed by an unmasked anisotropic etching of the partially etched spacer material layer. A related method for forming the uniform linewidth spacers uses a two-step anisotropic etch method that includes at least one masking process step.