发明授权
- 专利标题： Toll-like receptor agonist formulations and their use
- 专利标题（中）： Toll样受体激动剂配方及其用途
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申请号： US12533596申请日： 2009-07-31
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公开(公告)号： US08242106B2公开(公告)日： 2012-08-14
- 发明人: J. Jeffry Howbert , Muralikrishna Duvvuri , Robert Hershberg , Gregory Dietsch
- 申请人： J. Jeffry Howbert , Muralikrishna Duvvuri , Robert Hershberg , Gregory Dietsch
- 申请人地址： US WA Seattle
- 专利权人： VentiRx Pharmaceuticals, Inc.
- 当前专利权人： VentiRx Pharmaceuticals, Inc.
- 当前专利权人地址： US WA Seattle
- 代理机构： Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; Heidi A. Erlacher
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; C07D223/16
摘要：
The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer, preferably solid tumors and lymphomas. Specifically, the present invention is directed to stable formulations of up to 50 mg/ml of a TLR agonist which comprise a cyclodextrin.
公开/授权文献
- US20100029585A1 TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE 公开/授权日：2010-02-04
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