发明授权
US08257717B2 Immunogenic polypeptides encoded by MAGE minigenes and uses thereof
失效
由MAGE微生物编码的免疫原性多肽及其用途
- 专利标题： Immunogenic polypeptides encoded by MAGE minigenes and uses thereof
- 专利标题（中）： 由MAGE微生物编码的免疫原性多肽及其用途
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申请号： US12913271申请日： 2010-10-27
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公开(公告)号： US08257717B2公开(公告)日： 2012-09-04
- 发明人: Neil Berinstein , James Tartaglia , John A. Tine , Philippe Moingeon , Thierry Boon-Falleur , Pierre Vander Bruggen
- 申请人： Neil Berinstein , James Tartaglia , John A. Tine , Philippe Moingeon , Thierry Boon-Falleur , Pierre Vander Bruggen
- 申请人地址： CA BE
- 专利权人： Sanofi Pasteur Limited,Ludwig Institute for Cancer Research
- 当前专利权人： Sanofi Pasteur Limited,Ludwig Institute for Cancer Research
- 当前专利权人地址： CA BE
- 代理商 Patrick J. Halloran; Reza Yacoob
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N15/00 ; C12N15/86 ; C12N15/12 ; C12N15/861 ; C12N15/863 ; C07H21/04
摘要：
The invention discloses immunogenic polypeptides comprising several MAGE-specific antigen epitopes selected from different (i.e. discrete) members of the MAGE protein family, nucleic acids coding therefor, recombinant viruses and/or cells comprising said nucleic acids, and compositions thereof. Methods for eliciting or inducing MAGE-specific immune responses utilizing the aforementioned immunogenic agents are also disclosed.
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