Invention Grant
- Patent Title: Diazo bicyclic Smac mimetics and the uses thereof
- Patent Title (中): 重氮二环Smac模拟物及其用途
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Application No.: US12159249Application Date: 2008-04-14
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Publication No.: US08278293B2Publication Date: 2012-10-02
- Inventor: Shaomeng Wang , Yuefeng Peng , Haiying Sun , Qian Cai , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu
- Applicant: Shaomeng Wang , Yuefeng Peng , Haiying Sun , Qian Cai , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones SC
- International Application: PCT/US2008/060215 WO 20080414
- International Announcement: WO2008/128171 WO 20081023
- Main IPC: A61K31/33
- IPC: A61K31/33 ; C07D245/00
Abstract:
The invention relates to diazo bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
Public/Granted literature
- US20100273812A1 DIAZO BICYCLIC SMAC MIMETICS AND THE USES THEREOF Public/Granted day:2010-10-28
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