发明授权
- 专利标题： Immunomodulatory and anti-tumour peptides
- 专利标题（中）： 免疫调节和抗肿瘤肽
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申请号： US12278990申请日： 2007-02-23
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公开(公告)号： US08283324B2公开(公告)日： 2012-10-09
- 发明人: Maribel Guerra Vallespi , Isis del Carmen Torréns Madrazo , Osvaldo Reyes Acosta , Hilda Elisa Garay Pérez , Gerardo Enrique Guillén Nieto , Boris Ernesto Acevedo Castro , Raimundo Ubieta Gómez
- 申请人： Maribel Guerra Vallespi , Isis del Carmen Torréns Madrazo , Osvaldo Reyes Acosta , Hilda Elisa Garay Pérez , Gerardo Enrique Guillén Nieto , Boris Ernesto Acevedo Castro , Raimundo Ubieta Gómez
- 申请人地址： CU
- 专利权人： Centro de Ingenieria Genetica y Biotecnologia
- 当前专利权人： Centro de Ingenieria Genetica y Biotecnologia
- 当前专利权人地址： CU
- 代理机构： Hoffmann & Baron, LLP
- 优先权： CU47/06 20060224
- 国际申请： PCT/CU2007/000006 WO 20070223
- 国际公布： WO2007/095867 WO 20070830
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K14/00
摘要：
The present invention is related to the development of peptides derived from the sequence HYRIKPTFRRLKWKYKGKFW (SEQ ID NO.: 13), showing amino acid substitutions, these peptides unable to bind to the lipopolysaccharides and bearing anti-tumoral and immunomodulatory capacities. These peptides alone or in combination are useful to treat cancer, and also in synergy with conventional therapies.
公开/授权文献
- US20090221508A1 IMMUNOMODULATORY AND ANTI-TUMOUR PEPTIDES 公开/授权日：2009-09-03
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