发明授权
- 专利标题： Synthesis of boronic ester and acid compounds
- 专利标题（中）： 硼酸酯和酸化合物的合成
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申请号： US12706063申请日： 2010-02-16
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公开(公告)号： US08283467B2公开(公告)日： 2012-10-09
- 发明人: Vince Ammoscato , John E. Bishop , Fang-Ting Chiu , Achim Geiser , Jean-Marc Gomez , Robert Hett , Christoph Koellner , Vithalanand R. Kulkarni , Young Lo , Stephen Munk , I. Fraser Pickersgill
- 申请人： Vince Ammoscato , John E. Bishop , Fang-Ting Chiu , Achim Geiser , Jean-Marc Gomez , Robert Hett , Christoph Koellner , Vithalanand R. Kulkarni , Young Lo , Stephen Munk , I. Fraser Pickersgill
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Millennium Pharmaceuticals, Inc.
- 主分类号： C07F5/02
- IPC分类号： C07F5/02
摘要：
The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
公开/授权文献
- US20100174072A1 SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS 公开/授权日：2010-07-08
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