Invention Grant
- Patent Title: Method of preparing clarithromycin
- Patent Title (中): 克拉霉素的制备方法
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Application No.: US12770869Application Date: 2010-04-30
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Publication No.: US08288514B2Publication Date: 2012-10-16
- Inventor: Xintang Rao , Zhijian Ding , Hangbin Lou , Jing Wu , Yanglin Fang , Baineng Deng
- Applicant: Xintang Rao , Zhijian Ding , Hangbin Lou , Jing Wu , Yanglin Fang , Baineng Deng
- Applicant Address: CN Yiwu, Zhejiang Province
- Assignee: Zhejiang Huayi Pharmaceutical Co., Ltd.
- Current Assignee: Zhejiang Huayi Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Yiwu, Zhejiang Province
- Agency: Jacobson Holman PLLC
- Priority: CN200910098150 20090430
- Main IPC: C07H17/08
- IPC: C07H17/08
Abstract:
This invention discloses a method of manufacturing clarithromycin, where an erythromycin A 9-oxime thiocyanate salt is used directly to perform an etherification reaction, and then successively silanizattion, methylattion and hydrolysis reactions are sequentially conducted. It is a new process with simple process with a high yield, low cost, less pollution, high quality and is suitable for commercial manufacturing.
Public/Granted literature
- US20100280230A1 METHOD OF PREPARING CLARITHROMYCIN Public/Granted day:2010-11-04
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