Invention Grant
US08293763B2 8-anilinoimidazopyridines and their use as anti-cancer and/or anti-inflammatory agents
失效
8-苯胺基咪唑并吡啶类及其作为抗癌和/或抗炎剂的用途
- Patent Title: 8-anilinoimidazopyridines and their use as anti-cancer and/or anti-inflammatory agents
- Patent Title (中): 8-苯胺基咪唑并吡啶类及其作为抗癌和/或抗炎剂的用途
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Application No.: US12808346Application Date: 2008-12-18
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Publication No.: US08293763B2Publication Date: 2012-10-23
- Inventor: Stephen Price , Robert Heald , Pascal Pierre Alexandre Savy
- Applicant: Stephen Price , Robert Heald , Pascal Pierre Alexandre Savy
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Brian L. Buckwalter
- International Application: PCT/US2008/087476 WO 20081218
- International Announcement: WO2009/085980 WO 20090709
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/04 ; A61P35/00
Abstract:
The invention relates to imidazopyridines of formula I with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.(Formula I)
Public/Granted literature
- US20100280063A1 8-ANILINOIMIDAZOPYRIDINES AND THEIR USE AS ANTI-CANCER AND/OR ANTI-INFLAMMATORY AGENTS Public/Granted day:2010-11-04
Information query
IPC分类:
